Pipeline Products

Products in the Pipeline

ISurTec is expanding the application of our coatings to cell cultureware and in vitro Diagnostics. We have developed new coatings to meet the needs of the research market. Our latest coatings control the interaction of cells and biomolecules at the surface of the vial or plate wall.  If you don’t want cells to attach, use our ISurCell Ultra-Low Attachment plates.  If you want your cells to attach but come off at a given time, our ISurTherm Thermoresponsive Plates are for you!

These products are in beta testing – please contact us if you are interested in collaborating.

Pipeline Products

Products in the Pipeline

ISurTec is expanding the application of our coatings to cell cultureware and in vitro Diagnostics. We have developed new coatings to meet the needs of the research market. Our latest coatings control the interaction of cells and biomolecules at the surface of the vial or plate wall.  If you don’t want cells to attach, use our ISurCell Ultra-Low Attachment plates.  If you want your cells to attach but come off at a given time, our ISurTherm Thermoresponsive Plates are for you!

These products are in beta testing – please contact us if you are interested in collaborating.

Human dermal fibroblast spheroids on ISurCell 96-well plate

ISurCell ULA Cultureware

Ultra-low attachment cell cultureware for spheroid production and tissue engineering

ISurCell ULA cultureware promotes spheroid formation and long-term organoid culture. Available in 6-well, 12-well, 24-well, and 96-well formats. The ISurCell plates are coated with our proprietary ultra-low attachment coating on standard polystyrene.

Applications: ISurCell ULA plates can be used for a wide variety of applications such as creating tissue models for drug discovery and development, suspension cultures, and organoid technology.

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ISurCell ULA Cultureware

Ultra-low attachment cell cultureware for spheroid production and tissue engineering

ISurCell ULA cultureware promotes spheroid formation and long-term organoid culture. Available in 6-well, 12-well, 24-well, and 96-well formats. The ISurCell plates are coated with our proprietary ultra-low attachment coating on standard polystyrene.

Applications: ISurCell ULA plates can be used for a wide variety of applications such as creating tissue models for drug discovery and development, suspension cultures, and organoid technology.

Human dermal fibroblast spheroids on ISurCell 96-well plate
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Human dermal fibroblast (hDF) cells cultured on an ISurTherm plate for 48 hrs, forming a cell sheet during release after 20 minutes

ISurTherm® Cultureware

Thermoresponsive cell cultureware for non-enzymatic cell sheet release

ISurTherm cultureware has a proprietary thermoresponsive coating and is available to multiwell plate and flask formats. The use of these surfaces replaces the use of trypsin for collecting cells since detachment is achieved merely by lowering the culture temperature to ambient room temperature. This eliminates the need for trypsin; hence it saves on washing, labor, time, and proteolysis.

Applications: Ideally suited for the collection of viable cells with intact cell surface proteins and gap junctions without the use of digestive enzymes like trypsin or other harsh treatment.

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ISurTherm® Cultureware

Thermoresponsive cell cultureware for non-enzymatic cell sheet release

ISurTherm cultureware has a proprietary thermoresponsive coating and is available to multiwell plate and flask formats. The use of these surfaces replaces the use of trypsin for collecting cells since detachment is achieved merely by lowering the culture temperature to ambient room temperature. This eliminates the need for trypsin; hence it saves on washing, labor, time, and proteolysis.

Applications: Ideally suited for the collection of viable cells with intact cell surface proteins and gap junctions without the use of digestive enzymes like trypsin or other harsh treatment.

Human dermal fibroblast (hDF) cells cultured on an ISurTherm plate for 48 hrs, forming a cell sheet during release after 20 minutes
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Magnetic microparticles pellet and handle easier when your vial walls are treated with ISurBlock Solutions. The Eppendorf tube on the right was treated with an ISurBlock solution; the left is a standard untreated polypropylene Eppendorf tube. 

ISurBlock Solutions for Handling

Reduces sample loss to containers. Pretreat assay vials with ISurBlock, and enjoy much more manageable samples 

ISurBlock prevents adsorption of proteins to surfaces.  This means that samples will not stick to your vial, particles will not agglomerate to each other or stick to a vial wall, and sample handling is improved. ISurBlock does not interfere with assays or analysis because it is totally synthetic (non-animal) and highly reproducible.  It is easy to apply – simply pipet in the aqueous ISurBlock solution and incubate for 15 minutes, then rinse.  Applying ISurBlock minimizes unwanted small losses of sample during sample transfer and handling. 

Applications: Blocking treatment for assay vials, tubes, plates, and particles.  Any surface that suffers from non-specific protein adsorption can be improved by blocking with ISurBlock.

Beta Testing
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ISurBlock Solutions for Handling

Reduces sample loss to containers. Pretreat assay vials with ISurBlock, and enjoy much more manageable samples 

ISurBlock prevents adsorption of proteins to surfaces.  This means that samples will not stick to your vial, particles will not agglomerate to each other or stick to a vial wall, and sample handling is improved. ISurBlock does not interfere with assays or analysis because it is totally synthetic (non-animal) and highly reproducible.  It is easy to apply – simply pipet in the aqueous ISurBlock solution and incubate for 15 minutes, then rinse.  Applying ISurBlock minimizes unwanted small losses of sample during sample transfer and handling. 

Applications: Blocking treatment for assay vials, tubes, plates, and particles.  Any surface that suffers from non-specific protein adsorption can be improved by blocking with ISurBlock.

Magnetic microparticles pellet and handle easier when your vial walls are treated with ISurBlock Solutions. The Eppendorf tube on the right was treated with an ISurBlock solution; the left is a standard untreated polypropylene Eppendorf tube. 
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ISurBlock Solutions Block non-specific Antibody Adsorption on Magnetic Microbeads
ISurBlock Solutions block undesired background antibody adsorption to polystyrene magnetic microbeads better than traditional BSA blockers.

ISurBlock Solutions for Immunoassay

Passivate your immunoassay surfaces against non-specific adsorption with ISurBlock solutions. ISurBlock improves Signal/Noise while increasing reproducibility compared to BSA.

Applications: BSA substitute for immunoassays in multiwell plates, magnetic and latex microparticles, and on fibers, films, and gels.

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ISurBlock Solutions for Immunoassay

Passivate your immunoassay surfaces against non-specific adsorption with ISurBlock solutions. ISurBlock improves Signal/Noise while increasing reproducibility compared to BSA.

Applications: BSA substitute for immunoassays in multiwell plates, magnetic and latex microparticles, and on fibers, films, and gels.

ISurBlock Solutions Block non-specific Antibody Adsorption on Magnetic Microbeads
ISurBlock Solutions block undesired background antibody adsorption to polystyrene magnetic microbeads better than traditional BSA blockers.
Beta Testing
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EXPLORE R&D

EXPLORE R&D

ISurTec is a technology innovator with a deep passion for identifying, creating and commercializing new methods and products that enable companies to fulfill their mission.

CONTACT

Innovative Surface Technologies, Inc.
1045 Westgate Drive Suite 100
Saint Paul, MN 55114

651-209-9757

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ISurTec will consistently provide high-quality products and services that meet requirements for scientific, medical device, and industrial coatings. We will actively strive to bring excellence to the surface in all that we do, meeting or exceeding customers’ needs and expectations, and improve the quality of our products and service by enabling each employee to fulfill their job responsibilities correctly the first time.
The following are trademarks of ISurTec: ISurTec®, ISurGlide®, ISurLite®, ISurTherm®, ISurCoat®, PhotoPrime®, ISurGuard™, ISurBlock™, ISurCell™. All rights are expressly reserved.